Anti-TAB1(N-term) Monoclonal Antibody-抗体-抗体-生物在线

Anti-TAB1(N-term) Monoclonal Antibody

商家询价

产品名称： Anti-TAB1(N-term) Monoclonal Antibody

英文名称： Anti-TAB1(N-term) Monoclonal Antibody

产品编号： K001402M

产品价格： null

产品产地：北京

品牌商标： solarbio

更新时间： 2025-02-07T13:54:15

使用范围： WB

北京索莱宝科技有限公司

联系人 : 索莱宝-龚思雨
地址 : 北京市通州区中关村科技园区通州园金桥科技产业基地景盛南四街15号85A三层
邮编 : 101102
所在区域 : 北京
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邮箱 : 3193328036@qq.com
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产品详情

Anti-TAB1(N-term) Monoclonal Antibody
品牌：solarbio | 货号：K001402M
商品货号： 商品品牌： 规格 基本售价： 选择规格
K001402M-50ul solarbio 50ul 960.00元 
K001402M-100ul solarbio 100ul 1600.00元

商品货号：	商品品牌：	规格	基本售价：	选择规格
K001402M-50ul	solarbio	50ul	960.00元
K001402M-100ul	solarbio	100ul	1600.00元

英文名称 Anti-TAB1(N-term) Monoclonal Antibody
别名 3'-Tab1;MAP3K7IP1
应用 WB
稀释比例 WB 1:1000.
交叉反应 Human
蛋白分子量 55kDa
Gene ID 10454
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 unknown
免疫原 Purified recombinant human TAB1(N-terminus) protein fragments expressed in E.coli.
性状 液体
Public Immunogen Range Purified recombinant human TAB1(N-terminus) protein fragments expressed in E.coli.
Subcellular Locations Cytosol Nucleus
Swiss Prot Q15750
克隆号 3D10-G10-B6
克隆类型 Monoclonal Antibody
背景资料 The protein encoded by this gene was identified as a regulator of the MAP kinase kinase kinase MAP3K7/TAK1, which is known to mediate various intracellular signaling pathways, such as those induced by TGF beta, interleukin 1, and WNT-1. This protein interacts and thus activates TAK1 kinase. It has been shown that the C-terminal portion of this protein is sufficient for binding and activation of TAK1, while a portion of the N-terminus acts as a dominant-negative inhibitor of TGF beta, suggesting that this protein may function as a mediator between TGF beta receptors and TAK1. This protein can also interact with and activate the mitogen-activated protein kinase 14 (MAPK14/p38alpha), and thus represents an alternative activation pathway, in addition to the MAPKK pathways, which contributes to the biological responses of MAPK14 to various stimuli. Alternatively spliced transcript variants encoding distinct isoforms have been reported

英文名称	Anti-TAB1(N-term) Monoclonal Antibody
别名	3'-Tab1;MAP3K7IP1
应用	WB
稀释比例	WB 1:1000.
交叉反应	Human
蛋白分子量	55kDa
Gene ID	10454
保存	Store at -20°C. Avoid freeze / thaw cycles.
储存液	Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法	Affinity purification
亚型	unknown
免疫原	Purified recombinant human TAB1(N-terminus) protein fragments expressed in E.coli.
性状	液体
Public Immunogen Range	Purified recombinant human TAB1(N-terminus) protein fragments expressed in E.coli.
Subcellular Locations	Cytosol Nucleus
Swiss Prot	Q15750
克隆号	3D10-G10-B6
克隆类型	Monoclonal Antibody
背景资料	The protein encoded by this gene was identified as a regulator of the MAP kinase kinase kinase MAP3K7/TAK1, which is known to mediate various intracellular signaling pathways, such as those induced by TGF beta, interleukin 1, and WNT-1. This protein interacts and thus activates TAK1 kinase. It has been shown that the C-terminal portion of this protein is sufficient for binding and activation of TAK1, while a portion of the N-terminus acts as a dominant-negative inhibitor of TGF beta, suggesting that this protein may function as a mediator between TGF beta receptors and TAK1. This protein can also interact with and activate the mitogen-activated protein kinase 14 (MAPK14/p38alpha), and thus represents an alternative activation pathway, in addition to the MAPKK pathways, which contributes to the biological responses of MAPK14 to various stimuli. Alternatively spliced transcript variants encoding distinct isoforms have been reported