Anti-JNK1 Monoclonal Antibody-抗体-抗体-生物在线
北京索莱宝科技有限公司
Anti-JNK1 Monoclonal Antibody

Anti-JNK1 Monoclonal Antibody

商家询价

产品名称: Anti-JNK1 Monoclonal Antibody

英文名称: Anti-JNK1 Monoclonal Antibody

产品编号: K001441M

产品价格: null

产品产地: 北京

品牌商标: solarbio

更新时间: 2025-02-07T13:54:15

使用范围: WB IF

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Anti-JNK1 Monoclonal Antibody

品牌:solarbio | 货号:K001441M
商品货号:商品品牌:规格基本售价:选择规格
K001441M-50ulsolarbio50ul960.00元
K001441M-100ulsolarbio100ul1600.00元
英文名称Anti-JNK1 Monoclonal Antibody
别名JNK;JNK-46;JNK1;JNK1A2;JNK21B1/2;PRKM8;SAPK1;SAPK1c
应用WB IF
稀释比例WB 1:1000. IHC 1:100.
交叉反应Human Mouse Rat
蛋白分子量46/54kDa
Gene ID5599
保存Store at -20°C. Avoid freeze / thaw cycles.
储存液Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法Affinity purification
亚型IgG2a
免疫原Purified recombinant human JNK1 protein fragments expressed in E.coli.
性状液体
Public Immunogen RangePurified recombinant human JNK1 protein fragments expressed in E.coli.
Subcellular LocationsCytoplasm Nucleus
Swiss ProtP45983
克隆号1A4-C5-F11
克隆类型Monoclonal Antibody
背景资料The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Five alternatively spliced transcript variants encoding distinct isoforms have been reported.